ACYCLOVIR (Zovirax) is an antiviral drug. It slows the growth and spread of the herpes virus so that the body can fight off the infection. Acyclovir will not cure herpes, but it can lessen the symptoms of the infection.

Acyclovir is used to treat infections caused by herpes viruses. Illnesses caused by herpes viruses include genital herpes, cold sores, shingles, and chicken pox.

Acyclovir may also be used for purposes other than those listed in this medication guide.

Important information about acyclovir

Take acyclovir for the entire length of time prescribed by your doctor. Your symptoms may get better before the infection is completely treated.

Treatment with acyclovir should be started as soon as possible after the first appearance of symptoms (such as tingling, burning, blisters).

Herpes infections are contagious and you can infect other people, even while you are being treated with acyclovir. Avoid letting infected areas come into contact with other people. Avoid touching an infected area and then touching your eyes. Wash your hands frequently to prevent passing the infection to others.

Before taking acyclovir

Do not take this medicine if you are allergic to acyclovir or valacyclovir (Valtrex). Before taking acyclovir, tell your doctor if you are allergic to any drugs, or if you have kidney disease. You may need a dosage adjustment or special tests during treatment.

FDA pregnancy category B. Acyclovir is not expected to be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. Herpes virus can be passed from an infected mother to her baby during childbirth. If you have genital herpes, it is very important to prevent herpes lesions during your pregnancy so that you do not have a genital lesion when your baby is born. Acyclovir passes into breast milk and may harm a nursing infant. Do not take this medication without telling your doctor if you are breast-feeding a baby.

Dosage

Take acyclovir exactly as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor. Follow the directions on your prescription label.

Treatment with acyclovir should be started as soon as possible after the first appearance of symptoms (such as tingling, burning, blisters).

Take each dose with a full glass of water. Drink plenty of water while you are taking acyclovir to keep your kidneys working properly.

Acyclovir can be taken with or without food. Taking acyclovir with food may decrease stomach upset.

Shake the oral suspension (liquid) well just before you measure a dose. To be sure you get the correct dose, measure the liquid with a marked measuring spoon or medicine cup, not with a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one. Take acyclovir for the entire length of time prescribed by your doctor. Your symptoms may get better before the infection is completely treated. Acyclovir will not treat a viral infection such as the common cold or flu.

Lesions caused by herpes viruses should be kept as clean and dry as possible. Wearing loose clothing may help to prevent irritation of the lesions.

Store acyclovir at room temperature away from moisture and heat.

What happens if I miss a dose?

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at the next regularly scheduled time. Do not take extra medicine to make up the missed dose.
What happens if I overdose?

Seek emergency medical attention if you think you have used too much of this medicine.

Overdose symptoms may include seizure (convulsions), hallucinations, and urinating less than usual or not at all.

What should I avoid while taking acyclovir?

Herpes infections are contagious and you can infect other people, even while you are being treated with acyclovir. Avoid letting infected areas come into contact with other people. Avoid touching an infected area and then touching your eyes. Wash your hands frequently to prevent passing the infection to others.

Acyclovir will not prevent the spread of genital herpes. Avoid sexual intercourse or use a latex condom to prevent spreading the virus to others.

Get emergency medical help if you have any of these signs of an allergic reaction to acyclovir: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any of these serious side effects:

Less serious acyclovir side effects may include: nausea, vomiting, diarrhea, loss of appetite, stomach pain, headache, feeling light-headed, or swelling in your hands or feet.

Before taking acyclovir, tell your doctor if you are also taking probenecid (Benemid). If you are using probenecid, you may not be able to use acyclovir, or you may need dosage adjustments or special tests during treatment.

There may be other drugs that can affect acyclovir. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.